Zeynab Amanzadeh; Felor Zargari; Alireza Khalilaria
Abstract
Diabetes mellitus is a metabolic disorder that is created by hyperglycemia and impaired insulin secretion, resistance to insulin action or both. Researches show that aqueous extracts of white tea has an antioxidant properties but few studies have been conducted on the effects of diabetic and hyperlipidemic. ...
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Diabetes mellitus is a metabolic disorder that is created by hyperglycemia and impaired insulin secretion, resistance to insulin action or both. Researches show that aqueous extracts of white tea has an antioxidant properties but few studies have been conducted on the effects of diabetic and hyperlipidemic. The aim of this study was to evaluate the effect of aqueous extract of white tea on the lipid profile and blood glucose in streptozotocin-induced diabetic rats. In the experimental study, 32 male Wistar rats were randomly divided into 4 groups of 8 were; First group, control group that received standard diet and a daily 1ml of distilled water via gavage; the second group, streptozotocin-induced diabetic rats; the third group, healthy rats aqueous extract of white tea (1.5 percent) were consumed; the forth group, diabetic rats that were consumed aqueous extracts of white tea (1.5 percent). After the treatment period (30 days) to determine blood glucose levels and lipid profile was performed and the data were analyzed with SPSS software (P<0.05). A significant decreases in serum levels of glucose, LDL, cholesterol and triglyceride and significant increase in levels of HDL and weight were observed in the group receiving aqueous extract of white tea (P<0.05). The results showed that aqueous extracts of white tea decreases serum levels of glucose, triglycerides, total cholesterol, LDL and HDL cholesterol levels significantly (P<0.05). The aqueous extracts of white tea is effective for hyperglycemia and hyperlipidemia in diabetic rats.
